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PDR for Herbal Medicines, Fourth Edition

Thomson Healthcare, Inc.
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McGuffin M, Hobbs C, Upton R et al., American Herbal Products Association's Botanical Safety Handbook. CRC Press, Boca Raton, FL; 1997. Parnell N, Ellis H & Ciclitira P, Absence of toxicity of oats in patients with dermatitis herpetiformis. In: N Engl J Med; 338:1470-1471, 1998. Richter WO, Jacob BG & Schwandt P, Interaction between fibre and lovastatin. In: Lancet; 338(8768): 706, 1991. Schneider E, Losliche Silikate im griinen Hafer. In: ZPT 11 (4): 129. 1990. Willuhn G, Pflanzliche Dermatika. Eine kritische Ubersicht.. In: DAZ 132(37): 1873. 1992.

Adaptogens: Herbs for Strength, Stamina, and Stress Relief

David Winston, RH(AHG), and Steven Maimes
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The American Herbalists Guild represents the goals and voices of many clinical herbalists, the american herbal products association represents the voice of the herbal products industry, and the National Center for Complementary and Alternative Medicine, which is part of the National Institutes of Health, is doing research and providing information on complementary and alternative medicine (including medicinal herbs) to the general public. The future looks relatively bright for herbal medicine in the United States.
Food and Drug Administration both use the standard common names found in Herbs of Commerce, a publication of the american herbal products association, effective January 2006. These names are required on the labels of commercial dietary supplements. However, some herbalists prefer to use different names based on regional popularity and tradition. The names used throughout this book are primarily in harmony with Herbs of Commerce, with a few exceptions. ADAPTOGENS AND PHYTOCHEMICALS Pharmacology is the study of drugs and their effects on the human body.

Sugar Shock!: How Sweets and Simple Carbs Can Derail Your Life-- and How YouCan Get Back on Track

Connie Bennett, C.H.H.C. with Stephen T. Sinatra, M.D.
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On the other hand, stevia's many supporters, which include the american herbal products association, Herb Research Foundation, and the American Botanical Council, as well as integrative physicians and nutritionists, are quick to point out that stevia has been consumed safely by humans for centuries in South Korea, Thailand, Peru, Bolivia, Paraguay, Argentina, Brazil, New Zealand, and Japan, with no known complaints. Over the years, those who've spoken out in favor of stevia include Julian Whitaker, M.D., Dr. Andrew Weil, the late Dr. Atkins, Dr. Ann-Louise Gittleman, Dr. Joseph Mercola, Dr.

PDR for Herbal Medicines, Fourth Edition

Thomson Healthcare, Inc.
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McGuffin M, Hobbs C, Upton R et al (eds): The American Herbal Products Association's Botanical Safety Handbook: Guidelines for the Safe Use and Labeling for Herbs in Commerce. CRC Press, Boca Raton, FL. 1997. McTaggart F, Buckett L, Davidson R, et al: Preclinical and clinical pharmacology of rosuvastatin, a new 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitor. Am J Cardiol 87(suppl):28B-32B. 2001. Melzer R, Fricke U, Holzl J et al: Proanthrocyanidins from Hypericum perforatum - effects on isolated pig coronary arteries. Planta Med 55:572-573. 1988.

The Desktop Guide to Herbal Medicine: The Ultimate Multidisciplinary Reference to the Amazing Realm of Healing Plants, in a Quick-study, One-stop Guide

Brigitte Mars, A.H.G.
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This led the american herbal products association and the U.S. Food and Drug Administration to issue a press release warning of potential risk from use of chaparral and suggesting that sale of chaparral be suspended. After more research, there was found to be no basis for the warning, and sale of chaparral was reinstated in 1995. There are still some precautions to take, nevertheless. Avoid chaparral during pregnancy and also while nursing. Excess use may be detrimental to the liver, kidneys, and lymphs.

PDR for Herbal Medicines, Fourth Edition

Thomson Healthcare, Inc.
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Boswellia, in American Herbal Products Association's Botanical Safety Handbook: Guidelines for the Safe Use and Labeling for Herbs in Commerce. CRC Press, Boca Raton, FL, USA; p 21. 1997. Menon MK & Kar A. Analgesic and psychopharmacological effects of the gum resin of boswellia serrata. Planta Med; 19:333-341. 1971. Miiller-Bohn T. Chemie und Pharmakologie des Weihrauchs: Boswelliasauren gegen chronische Polyarthritis und Colitis ulcerosa. In: DAZ 136(48):4324-4325. 1996. Pfister-Hotz G. Phytotherapie in der Geriatrie. In: ZPT 18(3): 165-162. 1997. Rail B et al.
The German Commission E lists morning sickness associated with pregnancy as a contraindication, and the american herbal products association lists pregnancy as a contraindication; however, no clinical evidence has been found to substantiate any harmful effects to mother or fetus. Most research provides evidence that Ginger can be used and is effective in the treatment of morning sickness (Vutyavanich et al, 2001; Fischer-Rasmussen et al, 1990). Ginger tea administered to pregnant Sprague-Dawley rats resulted in double the number of fetal losses compared to the control group (p<0.05).

The Natural Pharmacy: Complete A-Z Reference to Natural Treatments for Common Health Conditions

Alan R. Gaby, M.D., Jonathan V. Wright, M.D., Forrest Batz, Pharm.D. Rick Chester, RPh., N.D., DipLAc. George Constantine, R.Ph., Ph.D. Linnea D. Thompson, Pharm.D., N.D.
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This concern is not raised in any other reference, and rhe american herbal products association classifies the herb as "class 1," an herb that can be safely consumed during pregnancy when used appropriately.14 Decoctions of bitter orange substantially increased blood levels of cyclosporine in pigs, causing toxicity.15 Bitter orange also inhibited human cytochrome P450 3A (CYP3A) in the test tube.16 This is an enzyme that helps the liver get rid of numerous toxins, and strongly affects metabolism of certain drugs.
Both the German Commission E monograph and the American Herbal Products Association's guide on herbal safety state that linden has no toxic effects.10,11 In fact, linden is considered safe for use in children12 and there are no known reasons to avoid it during pregnancy (page 363) and breast-feeding. LOBELIA Common name: Indian tobacco Botanical name: Lobelia inflata Parts used and where grown Lobelia grows throughout North America. The leaves are primarily used in herbal medicine.

The Healing Power of Rainforest Herbs: A Guide to Understanding and Using Herbal Medicinals

Leslie Taylor, ND
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The import ban was lifted in 1995 after much lobbying led by the american herbal products association and other industry leaders. This allowed stevia to be sold as a dietary supplement under legislation called the Dietary Supplement Health and Education Act of 1994. The FDA, in one of its more politically incorrect debacles, has ruled that Traditional Preparation stevia is presumed safe as a dietary supplement but is considered unsafe as a food additive. This incongruity openly protects the profit margins of the "sweetener giants.

Prescription for Nutritional Healing, 4th Edition: A Practical A-to-Z Reference to Drug-Free Remedies Using Vitamins, Minerals, Herbs & Food Supplements

Phyllis A. Balch, CNC
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Membership in trade groups such as the american herbal products association (www.ahpa.org), while not a stamp of approval, does indicate the company's recognition of industry standards. We recommend purchasing herbs sold by reputable companies that have been in the herb business for at least ten years. A number of manufacturers and distributors specializing in herbal products, including herbal combinations for prevention or treatment of certain disorders, are listed under Manufacturer and Distributor Information in the Appendix.

The Natural Pharmacy: Complete A-Z Reference to Natural Treatments for Common Health Conditions

Alan R. Gaby, M.D., Jonathan V. Wright, M.D., Forrest Batz, Pharm.D. Rick Chester, RPh., N.D., DipLAc. George Constantine, R.Ph., Ph.D. Linnea D. Thompson, Pharm.D., N.D.
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The German Commission E and american herbal products association both state there are no known risks with oregano leaf;12 neither of these references mentions oregano oil. Due to the lack of human research and the highly concentrated nature of oregano volatile oil, there is potential for harm from its use; therefore, until its internal use in humans has been proven safe, it should taken with caution if not recommended by a healthcare professional.13 Volatile oils are generally considered contraindicated in pregnancy (page 363) as they likely reach the baby and may cause harm.

Herbal Drugs and Phytopharmaceuticals: A Handbook for Practice on a Scientific Basis

Josef A. Brinckmann and Michael P. Lindenmaier
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Note: According to the American Herbal Products Association's (AHPA) Herbs of Commerce 2nd ed., the genus Cassia has been changed to Senna, and the separate species listed above are grouped together under one single classification, Senna alexandrina Mill., however, this new classification does not correspond to that of the Ph. Eur. Synonyms: Senna fruit, Cassia fruit (Engl.), Fruit de sene (Fr.), Sennes-fruchte, Sennesbalge or Sennesschoten (both expressions are botanically incorrect) (Ger.), Folliculi Sennae (Lat.), Fruto de sen (Span.). Origin: See: Sennae folium.

Medical Herbalism: The Science Principles and Practices Of Herbal Medicine

David Hoffman, FNIMH, AHG
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McGuffin, Hobbs, Upton, Goldberg, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, 1997. 4. Mclntyre A. The Herbal for Pregnancy and Childbirth. Shaftesbury, UK: Element Books, 1992. 5. Pizzorno JE, Murray MT. The Textbook of Natural Medicine. Edinburgh: Churchill Livingstone, 1999. Suggested Reading Gladstar R. Herbal Healing for Women. New York: Simon & Schuster, 1993. Green J. Male Herbal: Health Care for Men and Boys. Freedom, CA: Crossing Press, 1991. Hudson T. Women's Encyclopedia of Natural Medicine.

The ABC Clinical Guide to Herbs

Mark Blumenthal
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Data on the potential safety of senna was submitted by members of the OTC drug industry, thereby allowing senna-based laxative preparations to stay on the market until the FDA's determination is issued (FDA, 2002c).The american herbal products association and the International Aloe Science Council filed a petition with the FDA requesting a stay of this order until new safety data on aloe and cascara could be filed and considered (AHRA, 2002). FDA, there are numerous provisions in the FDCA and DSHEA that give the FDA adequate authority to remove unsafe supplements from the market: "...
McGuffin M, Hobbs C, Upton R, Goldberg A (eds.). American Herbal Products Association's Botanical Safety Handbook. Boca Raton: CRC Press; 1997. Medical Products Agency (MPA). Naturlakemedel: Authorised Natural Remedies (as of January 24, 2001). Uppsala, Sweden: Medical Products Agency; 2001. MPA. See: Medical Products Agency. Murch S, Simmons CB, Saxena PK. Melatonin in feverfew and other medicinal plants [letter]. Lancet 1997;350(9091): 1598-9. Murphy J, Heptinstall S, Mitchell J. Randomized double-blind placebo-controlled trial of feverfew in migraine prevention.
American Herbal Products Association (AH PA) has published a listing of about 1,650 herbs used in commerce in the U.S., with the "standardized common name" linked to the most recent Latin binomial; "other common names" are also noted, although they are not preferred (McGuffin etal., 2000). An earlier version of this self-regulatory initiative listing approximately 550 herbs was published in 1992 (Foster, 1992). In 1997, the U.S. Food and Drug Administration (FDA) adopted Herbs of Commerce as an official list for common names of herb products sold in the U.S. and thus federal regulations [21 C.
PREGNANCY AND LACTATION: No known restrictions according to the american herbal products association and the Commission E, but controlled, long-term safety studies are lacking. The BHC contraindicates ginseng in pregnancy, even though ginseng is not teratogenic in vivo. NOTE: In Traditional Chinese Medicine (TCM), ginseng root is included in prescriptions given during pregnancy, labor, and postpartum. Adverse Effects None known.
McGuffin M, Hobbs C, Upton R, Goldberg A. American Herbal Products Association's Botanical Safety Handbook: Guidelines for the Safe Use and Labeling for Herbs of Commerce. Boca Raton: CRC Press; 1997. Medical Products Agency (MPA). NaturlakemedeI: Authorised Natural Remedies (as of January 24, 2001). Uppsala, Sweden: Medical Products Agency. 2001a. Medical Products Agency (MPA). Lakemedel; Lakemedelsnara Produkter (registrerade homeopatiska produkter). Uppsala, Sweden: Medical Products Agency. 2001b. Misik V, Bezakova L, Malekova L, Kostalova D.

Disease Prevention and Treatment

The Life Extension Editorial Staff
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Because of the growing list of herb-dmg interactions, two regulatory groups, the american herbal products association (AHPA) and the Consumer Healthcare Products Association (CHPA), have made labeling recommendations that alert consumers not to combine St. John's Wort with prescription medication without first asking a health professional (HerbalGram 2000). St. John's Wort has been reported to aggravate mania, so it should be used with caution by individuals with bipolar disease. As with all antidepressants, St. John's Wort does not work for everyone with depression.

Rational Phytotherapy: A Reference Guide for Physicians and Pharmacists

volker schulz and Rudolf Hansel
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Europe The american herbal products association estimates that, based on sales figures provided by 14 companies, 6.8 billion dosage forms of ephedra dietary supplements were sold in the U.S. between 1995 and 1999 (McGuffin, 2000). As of 1999, the Food and Drug Administration (FDA) had recorded more than 2000 adverse events purportedly attributed to ephedra, but these were not evaluated as to degree of seriousness. All events resulting in illness or injury apparently associated with an ephedra product were listed.

Herbal Drugs and Phytopharmaceuticals: A Handbook for Practice on a Scientific Basis

Josef A. Brinckmann and Michael P. Lindenmaier
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S.: The american herbal products association recommends that all herbal products containing toxic pyrrolizidine alkaloids bear the following cautionary label statement: For external use only. Do not apply to broken or abraded skin. Do not use when nursing. Authentication: Macroscopic (see also: Description) and microscopic, following the Farfarae folium monograph of the DAB 1996, where butterbur leaves are described as an adulterant (see also [20]). Fig. 5 shows the typical, articulated covering trichomes.
Note: According to the American Herbal Products Association's (Ahpa) Herbs of Commerce 2nd ed, the genus Cassia has been changed to Senna, and the separate species listed above are grouped together under one single classification, Senna alexandrina Mill, however, this new classification does not correspond to the official monographs of the Ph. Eur, USP, and others. Synonyms: Sana (Arabic), Svamapatri (Ayur.), Fan xieje (Chin.), Cassia leaf (Engl.), Feuille de sene (Fr.), Sennesblatter (Ger.), Hoja de sen, Foliolo de sen (Span.), Sana, Sena (Unani).

The ABC Clinical Guide to Herbs

Mark Blumenthal
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Pharmazie 1999;54(3):210-5. fussel a, wolf a, brattstrom a. effect of a fixed valerian-hop extract combination (ze 9109) on sleep polygraphy in patients with non-organic insomnia: a pilot study Eur J Med Res 2000;5:385-90. gabor m, engi e, sonkodi s. the influence of water soluble flavonoid derivates on capillary resistance in hypertonic rats [in german]. Phlebologie 1993;(22): 178-82. gerhard u, linnenbrink n, georghiadou c, hobi v. vigilance-decreasing effects of 2 plant-derived sedatives. Schweiz Rundsch MedPrax 1996;85(15):473-81. gieldanowski j.

The One Earth Herbal Sourcebook: Everything You Need to Know About Chinese, Western, and Ayurvedic Herbal Treatments

Alan Keith Tillotson, Ph.D., A.H.G., D.Ay.
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It is entitled the Botanical Safety Handbook and is sponsored by the american herbal products association (AHPA). The book provides safety data for over 600 commonly used and prescribed herbs, with complete up-to-date information regarding international regulatory status, standard dosage, and certain common toxicity concerns. The AHPA web site accurately states: "The editors of this book are among the most respected leaders in the herbal products industry.

The Natural Pharmacy: Complete Home Reference to Natural Medicine

Schuyler W. Lininger, Jr. DC
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McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, 1997, 55. Rosemary 1. Castleman M. The Healing Herbs. New York: Bantam Books, 1991, 452-56. 2. Leung AY, Foster S. Encyclopedia of Common Natural Ingredients Used in Foods, Drugs, and Cosmetics, 2d ed. New York: John Wiley & Sons, 1996, 446-48. 3. Huhtanen C. Inhibition of Clostridium botulinum by spice extract and aliphatic alcohols. / Food Protect 1980; 43: 195-96. 4. Aqel MB.

Healing with Plants in the American and Mexican West

Margarita Artschwager Kay
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This led both the american herbal products association and the fda to ask that it be removed from the shelves of health food stores, although extensive chemical and pharmacological studies have failed to find any hepatotoxic properties in the tea (Blumenthal 1993^93-94). In February 1995, the ahpa rescinded the chaparral ban, creating a hotline ([512] 469-6344) for reporting adverse effects (HerbalGram 1995, vol. 35:23)- ¦ LigUSticum (Apiaceae) LOVAGE Ligusticum porteri Coult.

The Doctors Book of Home Remedies II: Over 1,200 New Doctor-Tested Tips and Techniques Anyone Can Use to Heal Hundreds of Everyday Health Problems

the Editors of PREVENTION
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Before you try the remedies in this book, check the following safety guidelines, based on the American Herbal Products Association's Botanical Safety Handbook, a recognized source of herb safety information, and on the advice of experienced herbal healers. Then you can enjoy the world of herbal healing with confidence. Herb Cautions and Safety Guidelines Agrimony (Agrimonia eupatoria) None; generally regarded as safe. Alfalfa (Medicago sativd) None; generally regarded as safe. Aloe (Aloe barbadensis) Do not use gel topically on any surgical incision; may delay wound healing.

Herbal Defense

Robyn Landis
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The new supplement law was intended to help preserve the rights of consumers to have access to authentic herbal medicines, not shield irresponsible products from regulation. The american herbal products association has acted quickly and vigorously when there is a question about a supplement, as you've seen in earlier examples. APHA developed a policy of label warnings and dose limits for ma huang products in 1994 and restricts their sale to those under eighteen.

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