| The chemical structure of astragaloside I from astragalus oleifolius.
^ JSO >° II ° OH
OH | * diroer 01 fh» (3,5- tfhydraxy - 6 - msthytoetenolc mold)
«V* 0*......0 >'• I4
P CHO «jf
8^ Apt
FIGURE 19.18. The chemical structure of QS 21 from Quillaja saponaria. antigens, and to have a relatively low toxicity in preclinical studies. QS 21 has been evaluated in a large number of vaccines in Phase 1 and II human clinical trials, including cancer immunotherapeutics, HIV recombinant envelopes, and malarial antigens. | | The extracts of astragalus appear to be safe, but suggestions of mutagenicity need to be examined further.
Bitter Melon
Bitter melon (Momordica charantia L., Cucurbitaceae family) has been confirmed to possess antiviral properties (against polio, herpes simplex 1, and HIV). The active constituent appears to be a 28.6 kD protein named MRK29 that inhibits HIV-1 reverse transcriptase.29 The bitter taste of this plant would be a disincentive for oral use, and there has been insufficient examination of MRK29 to establish whether its use would lead to hypersensitivity. | | Astrago-lus saponin I, a triterpene saponin, is isolated from astragalus membranaceus Bge. Esculentosides A, B, C, D, E, and F are also triterpene saponins isolated from Phytolacca esculenta Van Houlte. They have been considered to have anti-inflammatory action.33
Cardiac Glucosides
Peruvoside and neriifolin, isolated from the kernels of Thevetia perur-iana (Pers.) K. Schum, possess inotropic and toxic effects. | | Cycloartane saponins from astragalus peregrinus as modulators of lymphocyte proliferation, Fitoterapia, 72(8): 894-905.
83. Bernhardt, M., Sturm, C, Shaker, K.H., Paper, D.H., Franz, G., and Seifert, K., 2001, Structurally related immunological effects of triterpenoid saponins, Pharmazie, 56(9): 741-743.
84. Press, J.B., Reynolds, R.C., May, R.D., and Marciani, D.J., 2000, Structure/ function relationships of immunostimulating saponins, in Atta-ur-Rahman (ed.), Studies in natural products chemistry, Volume 24 (Amsterdam, The Netherlands: Elsevier, 2000), pp. 131-174.
85. Waite, D. | | An elderly patient with lung carcinoma was treated with the traditional Japanese herbal medicine Ninjin Yoei To, based on extracts of ginseng, cinnamon bark, angelica root, astragalus root, paeoni root, citrus peel, rehmannia root, polygala root, atractylodes rhizome, schisandra fruit, poria sclerotium, and glycyrrhiza. Treatment with the above at 15 g per day for seven weeks decreased the levels of tumor markers CEA and CA19-9, with an improved clinical status of the patent. | David Hoffman, FNIMH, AHG See book keywords and concepts | Tragacanth USP
Tragacanth is the gummy exudate from astragalus gum-mifer and other Asiatic species of astragalus.18 When introduced into water, tragacanth absorbs a certain proportion of that liquid, swells greatly, and forms a soft adhesive paste, but does not dissolve. If agitated with water, this paste forms a uniform mixture, but in the course of one or two days most of the tragacanth separates out and is deposited, leaving a portion dissolved in the supernatant fluid. Several days should be allowed in order to obtain a uniform mucilage of the maximum gel strength. | | Arctium lappa (burdock) astragalus membranaceus (astragalus) Calendula officinalis (calendula or pot marigold) Caulophyllum thalictroides (blue cohosh) Chionanthus virginicus (fringetree) Codonopsis spp. (codonopsis)
Digitalis purpurea (foxglove)
Dioscorea villosa (wild yam)
Eleutherococcus senticosus (Siberian ginseng)
Gentiana lutea (gentian)
Glycyrrhiza spp. (licorice)
Panax ginseng (Korean ginseng)
P. quinquefolius (American ginseng)
Phytolacca americana (poke)
Polygala senega (Seneca snakeroot)
Rumex crispus (yellow dock)
Salvia officinalis (sage)
Smilax spp. | Mike Adams, the Health Ranger See article keywords and concepts | Wolfe: Let's say the bird flu comes into your neighborhood or city or wherever you're at, and you start on the garlic, the echinacea, the lomatium, the reishi and the astragalus. You have all the superfoods, like the great vegetables and fruits. Your immune system is going to be able to knock it off. You're not going to get hit with it. It won't be able to hold onto you. Being prepared like that will literally save your life. Now, how much is it going to cost to have that tucked away in your herb cabinet? I'd say a maximum of $200. | Mike Adams, the Health Ranger See article keywords and concepts | Of course, once again, people in the know aren't going to be concerned about that because they'll be stocking up on elderberry extract and boosting their immune systems by taking herbs like astragalus, aloe vera, St. John's Wort, lemon balm herb and many others that have powerful antiviral properties.
My impression of the statements from governments around the world on bird flu is that they are basically designed to calm people down and are largely false statements. I fail to see how any country can be stocking up on a vaccine that doesn't even exist. | James F. Balch, M.D. and Mark Stengler, N.D. See book keywords and concepts | Do not take astragalus if you have a fever. Take 500 to 1,000 mg in capsule form or 3.0 ml of a tine-tare two to three times daily.
Thymus (Thymus vulgaris) extract optimizes immune activity. Take 1 to 2 capsules twice daily or as directed on the container.
Homeopathy
At the first signs of a flu, take 2 pellets of a 30C potency four times daily for three days, of the remedy that best matches your symptoms in this section. If you notice improvement, stop taking the remedy, unless symptoms return. If your symptoms do not improve within twenty-four hours, pick another remedy. | Mike Adams, the Health Ranger See article keywords and concepts | Another one I want to mention before we let this go is astragalus.
Mike: Oh, you bet.
Wolfe: That's one of the great Chinese herbs. It's a root, and it is considered one of the top six or seven herbs in the whole Chinese medicinal system, and that's another one that's an immune system modulator. If you need your immune system to go up, it will go up. If you need your immune system to calm down, it will go down. By the way, people will say, "Why do you need your immune system to calm down? | Michael Friedman, ND See book keywords and concepts | It has been used to treat wasting and thirsting conditions, as well as diarrhea, fatigue, and prolapse of the uterus. astragalus is used to control fluids in cases of excess sweating and to reduce fluid retention. In the Western world, the focus has been on its immunomodulatory effects, specifically the stimulation of interferon, which can be useful in conditions ranging from the common cold to cancer.58
Shatavari (Asparagus racemosus)
Shatavari is the common name of the Ayurvedic herb Asparagus racemosus horn the Liliaceae family. It translates as "she who possesses a hundred husbands. | Mike Adams, the Health Ranger See article keywords and concepts | Another one I want to mention before we let this go is astragalus.
Mike: Oh, you bet.
Wolfe: That's one of the great Chinese herbs. It's a root, and it is considered one of the top six or seven herbs in the whole Chinese medicinal system, and that's another one that's an immune system modulator. If you need your immune system to go up, it will go up. If you need your immune system to calm down, it will go down. By the way, people will say, "Why do you need your immune system to calm down? | | Wolfe: Let's say the bird flu comes into your neighborhood or city or wherever you're at, and you start on the garlic, the echinacea, the lomatium, the reishi and the astragalus. You have all the superfoods, like the great vegetables and fruits. Your immune system is going to be able to knock it off. You're not going to get hit with it. It won't be able to hold onto you. Being prepared like that will literally save your life. Now, how much is it going to cost to have that tucked away in your herb cabinet? I'd say a maximum of $200. | Mike Adams, the Health Ranger See article keywords and concepts | They've done some incredible studies with astragalus. Being an herbalist, I really wanted to add the right ingredients for prevention. It's all about prevention. It's all about healthy lifestyles.
Mike: You also have probiotics in this formula.
Lovejoy: Yes. It has 8.5 billion probiotics. People ask me all the time why we want to put probiotics in the formula, and why is it so important. It's really because so many people are taking antibiotics today. It takes out those beneficial bacteria. What happens when we take out those beneficial bacteria is we lose part of our immune system. | Michael T. Murray, N.D. See book keywords and concepts | In clinical studies in China, astragalus has been shown to reduce the incidence and shorten the course of the common cold.1
While astragalus does exert some antiviral activity, its main effect is to enhance interferon production and secretion. astragalus can be used at the following dose given three times a day for the common cold:
• Dried root (or as tea): 1 to 4 grams
• Tincture (1:5): 2 to 6 milliliters (1-1V2 teaspoons)
• Powdered solid extract (2:1): 250-500 milligrams
Diabetes
Diabetes is divided into two major categories: type I and type II. | | The Chinese value astragalus as a specific tonic for strengthening the body's resistance to disease. In clinical studies in China, astragalus has been shown to reduce the incidence and shorten the course of the common cold.1
While astragalus does exert some antiviral activity, its main effect is to enhance interferon production and secretion. | James F. Balch, M.D. and Mark Stengler, N.D. See book keywords and concepts | Do not take astragalus if you have a fever.
General Recommendations
Vitamin C enhances immune function for acute bronchitis and has anti-allergy benefits for chronic bronchitis. Vitamin C is particularly important for smokers. Take 500 to 1,000 mg three times daily.
Garlic (Allium sativum) has antimicrobial effects. Take 300 to 600 mg of garlic extract twice daily.
Bromelain has a natural anti-inflammatory effect and enhances the effectiveness of some antibiotics. Look for products standardized to 2,000 M.C.U. (milk-clotting units) per 1,000 mg or 1,200 G.D.U. | | Astragalus membranaceus) : for chronic, as well as acute, bronchitis. It ;s the body's general resistance to infection, tincture two or three times daily. Do not take
Super Prescription #7 Colloidal sil
Take one-half to 1 teaspoon, or as d five days. It has an antimicrobial eff ver
rected on the container, three times daily for set, especially for bacteria.
Testing
The following test helps assess poss bronchitis:
Food and environmental allergy
. | Mark Blumenthal See book keywords and concepts | Astragalus root JP (Astragalus membranaceus (Fisch.) Bge., Fabaceae); Asian ginseng root JP (Panaxginseng CA. Mey., Araliaceae); Atractylodes rhizome JP (Atractylodes lancea (Thunb.) DC, Asteraceae); Japanese angelica root JP (Angelica acutiloba Kitagawa, Apiaceae); Bupleurum root JP (Bupleurum falcatum L., Apiaceae); Jujube fruit JP (Zyzyphus jujuba Mill., Rhamnaceae); Citrus unshiu peel JP (Citrus unshiu Markovich, Rutaceae); Licorice root JP (Glycyrrhiza uralensis Fisch. | Alan R. Gaby, M.D., Jonathan V. Wright, M.D., Forrest Batz, Pharm.D. Rick Chester, RPh., N.D., DipLAc. George Constantine, R.Ph., Ph.D. Linnea D. Thompson, Pharm.D., N.D. See book keywords and concepts | Early clinical trials in China suggest astragalus (page 631) root might benefit people with chronic viral hepatitis, though it may take one to two months to see results.62 Textbooks on Chinese herbs recommend taking 9-15 grams of the crude herb per day in decoction form. A decoction is made by boiling the root in water for a few minutes and then brewing the tea.
Another Chinese herb, Chinese scullcap (page 658), might be useful for liver infections. However, the research on this is generally of low quality.63
Are there any side effects or interactions? | Joseph E. Mario See book keywords and concepts | Boost Immunity with 360 drops (12 droppersful) Echinacea daily; Goldenseal, and Astragalus; Black Cumin oil; 5 grams Garlic daily restoresNK activity in 6-
12 weeks; Chaparral, Lotus, Pansy, and Saguaro; Lomatia root; Cayenne;
Burdockkills HIV in vitro. Licorice extract Glycyrrhizin sulfate endowed by chemical modification with reverse transcriptase inhibition may counter Human Immunodeficiency Virus (HIV). Chinese Cucumber root's Protein Trichosanthin (Compound Q) kills only cells infected with HIV virus. Milk Thistle liver antioxidant. St. | Stephen T., M.D. Sinatra See book keywords and concepts | Consequently, astragalus could help relieve hay fever and other allergic conditions. I have personally used astragalus as a remedy for my seasonal hay fever.
In China, astragalus has also been used to treat cancer. It enhances the body's natural defense functions by stimulating the responsiveness of T cells.
Chamomile, Myrrh Gum, and Fenugreek
Three other botanicals I use are chamomile, myrrh gum, and fenugreek. Chamomile is heralded in Europe as a cure-all. Its gentle action makes it safe for use by both children and adults. It has calming, antispasmodic, and even anti-inflammatory effects. | Phyllis A. Balch, CNC See book keywords and concepts | Brain/nervous system Ashwagandha, astragalus, bayberry, bilberry, blessed thistle, blue cohosh, catnip, celery, chamomile, chaste tree, devil's claw, dong quai, eyebright, fennel, fenugreek, feverfew, ginger, ginseng, goldenseal, gotu kola, guarana, hops, jaborandi, kava kava, kudzu, lavender, lemongrass, licorice, marshmallow, motherwort, muira puama, oat straw, passionflower, peppermint, plantain, rosemary, sage, St. | Joseph E. Mario See book keywords and concepts | Enhances body metabolism and Chi energy (with astragalus); improves pulmonary breathing; strengthens the spleen; spurs Red blood cells, counters fatigue and exhaustion; has Saponins and Polysaccharides; enhances phagocytosis; lessens White blood cell losses in chemo- and radiation therapies. Improves poor appetite, for digestion and assim ilation, and counters thirst.
•COFFEE Seeds/beans/berries (Coffea arabica, liberica, and robustus/Congo) Rubia family; also called Capuccino, Espresso, Java, and Mocha. Stimulant, diuretic. | Alan R. Gaby, M.D., Jonathan V. Wright, M.D., Forrest Batz, Pharm.D. Rick Chester, RPh., N.D., DipLAc. George Constantine, R.Ph., Ph.D. Linnea D. Thompson, Pharm.D., N.D. See book keywords and concepts | However, much more research is needed to know whether astragalus is safe in lupus or any other autoimmune disease. forth). Symptoms may be mild or severe and can interfere with eating and walking.
Tardive Dyskinesia (TD) is a condition of abnormal, repetitive, uncontrollable movements that develop after a long-term use of so-called antipsychotic medications used to treat schizophrenia (page 393) and related psychiatric disorders. | Phyllis A. Balch, CNC See book keywords and concepts | Herbs
Q astragalus, echinacea, goldenseal, pau d'arco, and red clover aid in healing.
Caution: Do not take goldenseal on a daily basis for more than one week at a time, and do not use it during pregnancy. If you have a history of cardiovascular disease, diabetes, or glaucoma, use goldenseal only under a doctor's supervision.
Recommendations
Q Eat a diet consisting mainly of fresh vegetables and fruits, plus brown rice, raw seeds and nuts, turkey, white fish, and whole grains.
Q Avoid highly processed, fried, and junk foods, as well as chicken. | Gary Null, Ph.D. See book keywords and concepts | In patients suffering from leucopenia, 10 ml equaled to 15 g of astragalus twice per day for eight weeks led to an 82.76 percent rate of effectiveness. Patients receiving 10 ml equaled to 5 g of astragalus over the same schedule experienced a 47.3 percent rate of effectiveness. astragalus may benefit the digestive system, protect against liver injury, boost the immune system of lupus patients, counter alcohol-induced memory loss, improve sperm motility, and help heal burn injuries. | Andrew Pengelly See book keywords and concepts | Mimosaceae), gum tragacanthe, astragalus spp. (Fabaceae), and prunus gums, Prunus spp. (Rosaceae).
Seed gums are obtained from certain types of seed endosperms. They are common in the legume (Fabaceae) family, for example locust bean gum and tamarind gum.
OH astragaloglucan—branch-chained polysaccharide from astragalus spp.
Acacia gums
Although wattle bark (Acacia spp.) was used medicinally by indigenous Australians for coughs and colds, and to varying degrees for other ailments, it was popular among white settlers as a domestic medicine mainly for gastrointestinal complaints. |
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