Elson M. Haas, M.D.
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 An extract of the ginkgo biloba leaves has been tested and reported to be effective at reducing ischemic symptoms—vascular insufficiency associated with aging and atherosclerosis. ginkgo biloba appears to increase cerebral blood flow and thus help oxygenation; it also may inhibit platelet aggregation. In a study of geriatric patients, ginkgo was shown to reduce symptoms of vertigo, memory loss, tinnitus, and headache. In another study of lower limb claudication symptoms, ginkgo helped reduce pain and improve walking tolerance over the placebo group. |
Mark Hyman, M.D.
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 We also asked him to stop drinking alcohol, and prescribed three natural products: ginkgo biloba, ginseng, and argi-nine.
Arginine is an amino acid that has an effect similar to Viagra; it raises the levels of a compound called nitric oxide, which is a substance found throughout our bodies that causes a number of important physiological effects. One of these is vasodilation, or enlarging of the blood vessels. Because of this action, nitric oxide can lower blood pressure and improve male erections. By taking arginine, men can do both simultaneously. |
The Life Extension Editorial Staff
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 A study of the effects of bilobalide, the main constituent of the nonflavone fraction of ginkgo biloba, provided the first direct evidence that bilobalide can protect neurons against oxidative stress. Bilobalide may block the apoptosis in the early stage and then attenuate the elevation of c-Myc, p53, and Bax genes and activation of caspase-3 in cells (Zhou et al. 2000).
An article by Yao et al. |
| As a topical agent, it has been found to help telieve skin conditions, including dermatitis and eczema. ginkgo biloba in combination with beta-glucan has helped to alleviate contact dermati-tis (Castelli et al. 1998). An ingtedient from ginkgo has been shown to have a positive effect on asthma (Mahmoud et al. 2000) and significantly reduces airway hyporeactivity. In another study, the authors concluded that ginkgo was an effective dtug for relieving airway inflammation (Li et al. 1997). |
| V PRODUCT AVAILABILITY
Life Extension Mix, Life Extension Booster, Coenzyme Qig, trimethylglycine, Cognitex, ginkgo biloba, Natutal Prostate Formula, Bone Assure, ChronoForte, Life Extension Herbal Mix, DHEA, Vitamin K, Healthprin, and Super GLA/DHA can be ordered by telephoning (800) 544-4440 or by ordering online at www.lef.org.
Prostate Cancer
INTRODUCTION TO DR. STRUM'S PROSTATE CANCER UPDATE
When I was diagnosed with advanced prostate cancet in September 1991,1 thought my life, as I had envisioned it, was over. |
Gary Null
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 If it can be put down to an arterial blockage, ginkgo biloba, widely regarded as a memory tonic, can help increase circulation, as has been documented in European studies. If you take 240 milligrams (mg) of ginkgo daily, it should relieve impotence due to arterial blockage. ginkgo biloba is best taken as a standardized extract because the constituents are not readily assimilated by the body. It does not break down well with alcohol either so it's not effective as a tincture or crude extract. |
Earl L. Mindell, RPh, PhD with Virginia Hopkins, MA
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| The herb ginkgo biloba isn't just great for improving blood flow to the brain and improving memory, it improves blood flow everywhere! Let's find out more about natural remedies for impotence.
NATURAL REMEDIES FOR IMPOTENCE
Even if you haven't been diagnosed with atherosclerosis (clogged arteries), impotence is nearly always a sign that circulation in the penis isn't as good as it could be. See Chapter Nine on drugs for heart disease for natural remedies for better circulation. |
| The bioflavonoids in grapeseed extract and ginkgo biloba help strengthen blood vessels and improve blood flow to the extremities.
Calcium, long known to be important for bone health, may also help with weight loss, according to recent research by scientists at the
University of Vermont. Women who increased their calcium intake by as little as 130 mg a day showed an increased rate of weight loss compared to women whose calcium intake didn't increase. In-depth studies of fat cell function have shown that when calcium intake is too low, a hormone that causes bones to demineralize is released. |
Jack Challem
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 Extracts of the herb ginkgo biloba also might be beneficial, though the research has been conflicting. Ginkgo serves as both an antioxidant and as a dilator of blood vessels in the brain, improving blood circulation to neurons.
Some research indicates that the anti-inflammatory properties of omega-3 fish oils also can reduce the risk of neuroinflammation. Given the progressive nature of Alzheimer's disease, the emphasis should be on prevention or reversing its early stages. It is not likely that advanced Alzheimer's disease can be reversed because of extensive damage to brain cells. |
Richard P. Brown, M.D., and Patricia L. Gerbarg, M.D.
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 He had been given antioxidants and ginkgo biloba, as well as many standard medications. But nothing stopped the progression of his illness.
By the time Mary brought Jim to see Dick, he was unable to finish sentences and was constantly drifting off to sleep. He was so disoriented that he required 24-hour supervision.
Dick treated Jim with a special formula called Clear Mind, which contains a blend of Rhodiola rosea, hydroxycinnamic acid from blueberries, and Rhododendron caucasicum. |
Ray Strand, M.D.
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 Many herbalists and researchers believe it improves one's ability to think and boosts stamina as a result of this increased blood flow. But ginkgo biloba has an additional effect of thinning the blood, which can lead to serious complications if a person is also taking aspirin or Coumadin.17
Many herbs that patients use work very similarly to prescription sedatives such as Ativan, Xanax, and Librium. The two most common herbs are valerian root and Kava Kava. |
Richard P. Brown, M.D., and Patricia L. Gerbarg, M.D.
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| John's wort, and ginkgo biloba. Dick added Rhodiola rosea to her existing regimen, which quickly calmed her down. Soon after, she was back at work, creating more complex designs with fewer mistakes than she had been able to since her accident. Two months later, she reported feeling "fantastic."
Now that Cheryl has added galanthus to her regimen, she's getting even better results. On her own, she has found ways to compensate for residual short-term memory loss. She has reestablished her strong social network, too. |
Earl L. Mindell, RPh, PhD with Virginia Hopkins, MA
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| To aid in healing carpal tunnel, in addition to 50 to 100 mg of vitamin B6 daily you can take ginkgo biloba to improve blood supply to the affected area. Since ginkgo improves circulation to the extremities, it seems a logical choice for CTS. You can also try taking glucosamine or EV.EXT77, since they aid the body in repairing cartilage and tendons.
CHAPTER THIRTEEN
Antibiotics, Antifungals, and Their Natural Alternatives
Anti-infectives is the general term to describe the drugs we take to fight all kinds of infections such as bacteria, fungus, parasites, and viruses. |
The Life Extension Editorial Staff
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| Grape-Seed Extract: 100 mg, once or twice daily, to supplement the similar agents already present in the Life Extension Mix
10. Ginkgo biloba: 120 mg daily
11. Beta-Glucan: two 100-mg capsules 30 minutes before meals
12. Cordyceps sinensis, two 500-mg capsules twice daily, with meals
13. Saccharomyces boulardii, 1-3 capsules daily (containing 1 billion live cells)
14- Glutamine, an initial dose of 3000-4000 mg (about 1 tsp), 2-3 times a day should be used. Higher doses may be safely used under a physician's supervision. |
Jack Challem
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| Among these are the herb ginkgo biloba and garlic. Lycopene, a carotenoid that gives tomatoes their red color, has been associated with a relatively low risk of stomach cancer, though this association does not directly prove prevention. In addition, animal experiments suggest that food allergies also might irritate the stomach and lead to gastritis and ulcers.
An estimated 30 percent of people over age sixty-five suffer from atrophic gastritis, a chronic inflammation of the stomach associated with a wasting away of stomach tissues. |
Heather Boon, BScPhm, PhD and Michael Smith, BPharm, MRPharmS, ND
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 Kleijnen and Knipschild reviewed 40 controlled trials studying the use of ginkgo biloba in cases of "cerebral insufficiency,"3 concluding that although only 8 trials were of "good quality,"78 85 all the trials reviewed, except one,86 showed clinically-relevant positive effects for ginkgo when compared with a placebo. |
| In an animal study, ginkgo biloba extract was found to be comparable to methylprednisone and more effective than thyroid releasing hormone at providing a protective effect against ischaemic spinal cord injury. This effect was thought to be due to its antioxidant actions.52
In addition, ginkgo has been shown to protect healthy volunteers from the effects of hypoxia.57 Animal studies have confirmed this finding. |
| For example, in an open trial of 112 patients suffering from symptoms of "chronic cerebral insufficiency" (mean age 71 years) taking 40 mg ginkgo biloba extract three times daily for one year, significant improvements in short-term memory, alertness, mood disturbances, vertigo, headaches and tinnitus were reported.78 A more recent double-blind, placebo-controlled trial of 90 patients suffering from "cerebral insufficiency" found that those taking ginkgo scored significantly higher on a variety of tests of cognitive function. |
| Depression
One randomized, placebo-controlled trial with 40 patients diagnosed with resistant depression (aged 51 to 78 years) found that ginkgo biloba extract (EGb 761) was significantly more effective than placebo. Patients in the trial had shown insufficient improvement on tri- and/or tetracyclic antidepressants for a minimum of three months prior to being enrolled in the trial. During the trial, patients continued to take anti-depressant therapy, but were also given either EGb 761 (80 mg) or placebo three times daily. |
| The authors concluded that "Ginkgo biloba extract is superior to placebo in the symptomatic treatment of intermittent claudication. However, the size of the overall treatment effect is modest and of uncertain clinical relevance."88 Kleijnen and Knipschild also reviewed 15 placebo-controlled trials which investigated the use of ginkgo extracts in the treatment of intermittant claudication.3 They report that only two were of "acceptable" quality,9197 and that all fifteen indicated positive effects for treatment with ginkgo. |
Linda B. White, M.D.
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 His regimen might include ginkgo biloba for memory and vision, saw palmetto for his prostate, garlic to keep his cholesterol low, Siberian ginseng for energy and overall well-being, bilberry for eyesight and circulation, milk thistle to protect his liver, and kelp to stimulate his thyroid. This typical man might also want to take an iron-free multivitamin, coenzyme Q10, and three key antioxidants—vitamin C, vitamin E, and selenium.
A typical woman of the same age might also want to take the ginkgo biloba, garlic, Siberian ginseng, and bilberry. |
Walter Last
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 For herbs, consider bromelain, ginger (with most meals), ginkgo biloba, and green tea; also helpful are digestive enzymes high in lipase. additional therapies: Remove any dead teeth and make sure there is no chronic jawbone infection in the wisdom tooth positions. Get regular exercise; have alternating hot and cold showers; and do skin brushing. Frequently press into the fleshy pad below the left thumb; pressing strongly here during a heart attack can allegedly stop the attack. |
Michael Janson, M.D.
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 Most of the scientific studies on ginkgo biloba have been done with a 24% standardized extract, not the plain powdered leaf. Capsules of the powdered leaf are also available, but the level of active components is not as consistent as in the standardized product.
Capsules of the 24% standardized ginkgo biloba extract are available in 40- to 60-mg sizes. I usually recommend taking about 120 mg per day (two or three capsules depending on the size), although I have sometimes recommended higher doses. |
volker schulz and Rudolf Hansel
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 The last surviving member of the family Ginkgoaceae, ginkgo biloba is unrelated to any other plant species alive today. The foliage of the ginkgo tree more closely resembles that of certain ferns than that of deciduous trees, its fan-shaped leaves lacking the central rib and cross venation seen in broad-leaf trees.
QE1 Crude Drug and Extract
The dried green leaves of the ginkgo tree provide the crude drug from which ginkgo extracts are obtained. Leaves may be gathered from cultivated trees or from the wild. |
Walter Last
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| For attention deficit, try ginkgo biloba.
Infections and Inflammations: Infections can be localized, for example, in the liver or throat, or generalized, as infectious diseases (including venereal diseases). They can be acute with sudden strong inflammations and fever, or they can be chronic and long lasting. Colds occur only if there is mucus congestion, and they are usually beneficial for removing excess mucus. Accelerate recovery by actively expelling mucus from your lungs and head spaces, including the sinuses. |
Earl L. Mindell, R.Ph., Ph.D.
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 Ginkgo biloba takes time to produce its effects and should be taken in repeated doses for a fairly long period of time. ginkgo biloba extract (GBE) with at least 24 percent ginkgoflavoglycosides, is the best form to take. Standardized, semi-purified and concentrated, GBE provides consistent levels of its most active compounds. Take the recommended dosage on the package.
Glutathione, also known as GSH, is a tripeptide made from the amino acids cysteine, glycine and glutamic acid. |
Walter Last
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| Before breakfast have strong coffee and tyrosine; with breakfast have bee pollen, spirulina or chlorella, ground linseed, sprouted broad beans, ginkgo biloba, ginseng, and other stimulating measures; reintroduce levodopa drugs as late as possible in the day. If levodopa has become ineffective, have a "drug holiday"—stop using it for one or more weeks. Try breathing additional oxygen during this time (e.g., from an oxygen concentrator); however, additional oxygen is harmful while you're on levodopa. See the Love Cure (step 61) and learn to meditate and energize the brain. |
Earl L. Mindell, RPh, PhD with Virginia Hopkins, MA
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| The most important supplements for strong blood vessels are the bioflavonoids, including grape-seed extract, rutin, hesperidin, ginkgo biloba, green tea, and bilberry. Supplements important for healthy, "slippery" blood (follow dosage recommendations for daily vitamins in this book) include magnesium, vitamin B6, folic acid, vitamin B12, vitamin E, selenium, N-acetyl cysteine, lysine, and garlic.
If you have high levels of vitamin C, your risk of dying from a stroke may be half that of those with lower levels. |
Patrick Holford
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 BRAIN-FOOD FORMULAS
I also supplement a complex of brain-friendly nutrients that includes phosphatidyl choline, phosphatidyl serine, DMAE, pyroglutamate, ginkgo biloba, plus extra B vitamins. Together with omega-3 fats, these give me optimum nutrition for the mind.
You will also find supplements that help support hormonal health, mood, energy, and relaxation. My book Natural Highs explains how to use nutrients and herbs to keep you calm and connected.
INDIVIDUAL NUTRIENTS
Sometimes even the above formulas may still leave you short on specific nutrients. |
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