Gary Null, Ph.D.
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 Feverfew
Feverfew has exhibited evidence of anti-thrombotic potential and inhibits platelet aggregation in vitro. feverfew extract has exhibited anti-candida activity in vitro. Daily consumption of fresh feverfew leaves can also prevent migraines.
Flaxseed Oil
Results of animal studies point to the anti-tumor activity of flaxseed with respect to colon and breast cancer. The consumption of 40 g per day of flaxseed oil over a period of twenty-three days has also been shown to have cardioprotective effects in healthy young men. |
Alan R. Gaby, M.D., Jonathan V. Wright, M.D., Forrest Batz, Pharm.D. Rick Chester, RPh., N.D., DipLAc. George Constantine, R.Ph., Ph.D. Linnea D. Thompson, Pharm.D., N.D.
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 Studies suggest that taking standardized feverfew leaf extracts that supply a minimum of 250 meg of parthenolide per day is most effective. Results may not be evident for at least four to six weeks. Although thete has been recent debate about the relevance of parthenolide as an active constituent,54 it is best to use standardized extracts of feverfew until research proves otherwise.
Anecdotal evidence suggests ginger (page 680) may be used for migraines and the accompanying nausea. |
Jonathan V. Wright, M.D. and Alan R. Gaby, M.D.
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 And what's feverfew? Sounds like maybe an aspirin."
"Recently, researchers reported that large quantities of riboflavin—vitamin B2—can prevent a significant proportion of migraines; better than half. feverfew is an herb—a botanical that has also been found to prevent migraines."
"So what's this about screening them and the other supplements, if they're supposed to help relieve migraine? Could they cause migraines, too?
"Anything you're allergic to can trigger a migraine—even if it's something that usually helps."
"OK." She got up to go. |
Thomson Healthcare, Inc.
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 Production: feverfew leaves are the leaves of Tanacetum parthenium. The plant is cut before full flowering. It is dried in thin layers in the shade, at temperatures not exceeding 35° C.
Other Names: Featherfew, Featherfoil, Midsummer Daisy actions and pharmacology
COMPOUNDS
Volatile oil (0. |
Jonny Bowden, Ph.D., C.N.S.
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 Beneficial Herbs
Two herbs stand out when it comes to treating migraines: butterbur (Petasites hybridus) and feverfew (Tanacetum parthenium). Compelling evidence from human trials suggests that butterbur may have real benefits in preventing migraines. One hundred and eight children and adolescents between the ages of six and seventeen tried butterbur root extract for four months and experienced a decrease in the frequency of migraine attacks. In addition, they all reported feeling better.
The same results were found in adults. |
Dr. Michael Heinrich, Joanne Barnes, Simon Gibbons and Elizabeth M. Williamson
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 Pharmacological effects and clinical efficacy
The main use of feverfew today is as a prophylactic and treatment for migraine, for which several clinical trials have shown it to be effective. In one study, 57 patients were included in a randomized, double-blind, placebo-controlled trial using capsules containing powdered feverfew leaves. They took the daily equivalent of 0.2 mg parthenolide for 60 days, then randomization to placebo and feverfew for 30 days, and then cross-over to the other
Parthenolide
Fig. 16.7 arm for another 30 days. |
Thomson Healthcare, Inc.
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| Occupational or direct exposure has caused eczema and allergic dermatitis. feverfew has been known to cross-react with Tansy, Yarrow, Marguerite, Aster, Sunflower, Laurel, and Liverwort (Schmidt, 1986; Guin & Skidmore, 1987; Paulsen, 1998). Other adverse reactions include abdominal pain, diarrhea, lip swelling, mouth ulcers (from chewing leaf), and glossitis (from chewing leaf) (Klepser & Klepser, 1999; Murdoch, 1989; deSmet & Vulto, 1987).
Cardiovascular: Transient increases in heart rate have occasionally been reported (Murdoch, 1989). |
Jonathan V. Wright, M.D. and Alan R. Gaby, M.D.
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| In another double-blind study, 59 patients with migraines were randomly assigned to receive 1 capsule of dried feverfew leaves per day or a placebo for 4 months. Each patient then received the alternate treatment for an additional 4 months. The number of migraine attacks was significantly reduced by 24% during the feverfew period, compared with the placebo period.14
Other Factors
Other factors that may trigger or aggravate migraines include cigarette smoking, use of oral contraceptives, emotional stress, and spinal misalignments. |
Joerg Gruenwald, Ph.D.
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| Production: feverfew leaves are the leaves of Chrysanthemum parthenium. The plant is cut before full flowering. It is dried in thin layers in the shade, at temperatures not exceeding 35°C. |
Earl L. Mindell, R.Ph., Ph.D.
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 Feverfew (Chrysanthemum parthenium): Nearly 2,000 years ago, the Roman doctor Dioscorides, one of the first to write a medical textbook, recommended the herb feverfew for headaches. feverfew is still the most effective treatment known for migraines. It is the only medicine that will help migraine headaches without side effects. This member of the daisy family is also called bachelor's buttons. feverfew has undergone much testing and research as a migraine remedy as pharmaceutical companies try to find the active ingredient so they can isolate it and synthesize it. |
Josef A. Brinckmann and Michael P. Lindenmaier
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 A conclusive opinion regarding the suitability of feverfew for the prophylaxis of migraine appears to not yet be possible [13]. The essential oil has shown marked antimicrobial effects [1]. In folk medicine, feverfew is also used for dysmenorrhea, uterine inertia, threatened miscarriage (hence the German name "Mutterkraut"), fever (hence the English name "feverfew"), toothaches, and as a tonic and stomachic.
Side effects: In rare cases, inflammations of the oral mucosa, digestive discomforts, and abdominal pain.
Making the tea: Pour boiling water over about two teaspoonfuls. |
Brigitte Mars, A.H.G.
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 The common name feverfew derives from the Latin febrifuga, "to chase away fevers," in reference to the plant's medicinal use. |
Tori Hudson, N.D.
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 Other botanicals might be considered for their anti-inflammatory properties, such as licorice {Glycerrhiza glabra) and feverfew {Tanacetumparthenium). Botanicals with demulcent properties allow for mucosal protection and soothing. These include licorice, slippery elm {Ulmus fulva), marshmallow (Althea officinalis), oat seed (Avena sativa), and comfrey {Symphytum officinale).
It can be crucial to use herbs that provide pain relief while the other therapies attempt to repair the lining of the bladder. |
Jonny Bowden, Ph.D., C.N.S.
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| HTP: 200-600 mg
Combo herbs: Butterbur, 50 to 150 mg; feverfew, 300 mg, twice daily for 12 weeks; white willow bark (300 mg, twice daily for 12 weeks)
Diet: Avoid refined sugar, alcohol, caffeine, aspartame, smoking, salt, and tyramine-containing foods
Reduce stress and get enough sleep Check for food allergies
Note: The dosages are daily and in pill or capsule form unless otherwise noted. varied, and differs from person to person. Some of the usual suspects include anxiety, stress, lack of food, lack of sleep, exposure to light, and hormonal changes in women. |
Marshall Editions
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 Taking regular aspirin or NSAIDs and certain herbs such as ginkgo, ginger, ginseng, garlic, and feverfew may predispose some people to easy bruising as can very high doses of certain supplements (for example, more than 3 g a day of Vtiamin C, or more than 6 g a day of fish oil). In other cases, a coagulation or clotting disorder may be present and should be evaluated. Such disorders are often genetic and most (but not all) are mild. They are diagnosed by blood tests. |
Amarjit S. Basra
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 Feverfew
In the United Kingdom, Canada, and some other countries, the dried leaves of feverfew Tanacetum parthenium (L.) Schultz Bip (Asteraceae) are used extensively as an herbal prophylactic for migraine headaches. This use is based on folklore but has been underpinned by several positive clinical studies.22 The nature of the compounds responsible is not very clear. At first it was thought that the sesquiterpene lactones, especially parthenolide (see Figure 17. |
David Winston, RH(AHG), and Steven Maimes
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 Other herbs have an unpleasant taste (saw palmetto, feverfew, valerian), and getting patients to drink cupfuls of a noxious-tasting brew will limit patient compliance. Some patients also will find having to make teas too time-consuming or impractical.
Tinctures are extracts of herbs in a mixture of alcohol and water. While not very concentrated (1:5 weight/volume), tinctures have the benefits of being a liquid. |
Dr. Julian Whitaker
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| We know that a phytochemical in feverfew called parthenolide gives the herb its headache-prevention properties. We also know from the research on feverfew that the most effective feverfew preparations contain 0.4- to 0.7-percent parthenolide. Therefore, a feverfew product standardized to contain 0.4- to 0.7-percent parthenolide is the most reliable product. Look for standardized extracts in all herbs. They're becoming more and more commonplace.
Insist on Quality Control
Herbs should be thoroughly tested and analyzed during harvesting and manufacturing. |
Jonny Bowden, Ph.D., C.N.S.
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| Using feverfew together with another herb, white willow bark, also reduces the frequency, intensity, and duration of migraine attacks, by up to 60 percent.
Vitamin B6, Magnesium, and Evening Primrose Oil
A Natural Cure for PMS
LET ME BE perfectly honest. As a man who has been on this planet for more than a few decades, I've lived with my share of women prior to meeting the love of my life, with whom I'm now happily living.
Vitamin B6
Melatonin
I've experienced PMS—on the receiving end of the spectrum—in many of its forms and intensities with a variety of women. |
Joerg Gruenwald, Ph.D.
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| DOSAGE
Mode of Administration: feverfew preparations are used both internally and externally.
Preparation: To make an infusion, use 2 teaspoonfuls of the drug per cup, allow to draw for 15 minutes. To make a strong infusion, double the amount and allow to draw for 25 minutes.
Dosage: The recommended daily dosage is 50 mg to 1.2 gm of leaf powder. In folk medicine, 3 cups of the infusion are taken per day. The stronger infusions are used for washes.
Storage: Store in sealed containers.
LITERATURE
Abad MJ, Berjemo P, Villar A, Phytother Res 9:79-92. 1995. |
Amarjit S. Basra
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| Randomised, double-blind, placebo-controlled trial of feverfew in migraine prevention, Lancet, 2: 189-192.
23. De Weerdt, C.J., Bootsma, H.P.R., and Hendriks, H., 1996, Herbal medicines in migraine prevention: Randomized double-blind placebo-controlled crossover trial of a feverfew preparation, Phytomedicine, 3: 225-230.
24. Spinella, 2001, The psychopharmacology of herbal medicine; Mills and Bone, 2000, Principles and practice of phytotherapy; Barnest, Anderson, and Phillipson. 2002, Herbal medicines: Farnsworth, N.R., Kinghorn, A.D., Soejarto. D.D., and Waller, D.P. |
Marshall Editions
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| Magnesium aspartate and B vitamins, especially niacin, along with the herbs butterbur and feverfew have been shown to be effective in treating migraines. Acupuncture and chiropractic treatment may also be worthwhile.
TRADITIONAL CHINESE MEDICINE
Herbs: The herbs listed in the formulas below are available from Chinese pharmacies or online. For each formula, make a decoction by mixing the herbs in a ceramic pot and adding 3 cups of water. Bring the herbs to a boil and simmer for 30 minutes. Strain the liquid and drink 1 cup twice a day. |
| Herbs: feverfew has been shown to reduce the duration and frequency of headaches. Take 250-500 meg daily of a product standardized to contain parthenolides. You can also try applying peppermint and menthol cream to the temple area to relieve tension headaches. Take 60-120 mg of white willow bark a day as it is an effective pain reliever. Ginger has anti-inflammatory benefits and relieves pain. Take 1-2 g or 1-2 ml of a tincture three times a day.
TIP: PEPPERMINT OR LAVENDER OIL COMPRESS
Peppermint or lavender oil can help relieve pain in some patients. |
Gary Null and Amy McDonald
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 Even when they have headaches, they tend to be less frequent and less painful." feverfew should not be used by pregnant women.
Dr. |
Marshall Editions
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| Clinical studies have shown feverfew to effectively treat and reduce the frequency of migraines when 100 mg of the dried herb, standardized to contain at least 0.6 mg of parthenolide, is taken twice daily. You can also take 1-2 ml of 1:5 dried plant tincture per day. Side effects are rare, but include mouth ulcers (from fresh leaves), indigestion, and diarrhea.
662
DIAGNOSIS
A muscle cramp is the result of an involuntarily contracted muscle that does not relax. |
Gary Null and Amy McDonald
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| Then you start to rebuild the brain and the center of the brain with phosphatidyl serine, acetyl-l-carnitine, phosphatidyl choline, and herbs that are known to have an impact, like feverfew and green tea. You flood the body with flavonoids. And don't forget the juice—four to six juices a day from fresh organic vegetables. After six months to a year of this regimen, I've seen about 80 percent of addicts cleared up, staying off it, and not coming back.
I would add that if you have a problem drinker in your family, one of the things you can do is just try to see that they take some vitamins. |
Marshall Editions
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| Herbs: feverfew has been shown to reduce the duration and frequency of migraines. Take 250-500 mg daily of a product standardized to contain parthenolides. White willow bark is an effective pain reliever and can be taken at 60-120 mg a day. Also take 1-2 g of ginger, or 1-2 ml of a tincture, three times a day for its anti-inflammatory benefits and ability to relieve pain. Do not take more than 1 g of ginger a day if you are pregnant. |
Earl L. Mindell, RPh, PhD with Virginia Hopkins, MA
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| Nearly 2,000 years ago, the Roman doctor Dioscorides, one of the first to write a medical textbook, recommended the herb feverfew {Chrysanthemum parthenium) for headaches. feverfew is still the most effective treatment known for migraines. It is the only medicine that will help migraine headaches without side effects. This member of the daisy family is also called bachelor's buttons. feverfew has undergone much testing and research as a migraine remedy as pharmaceutical companies try to find the active ingredient so they can isolate it and synthesize it. |
Marshall Editions
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| If you are on blood-thinning medications, such as warfarin or asprin, or a herbal supplement that affects bleeding, such as ginger, garlic, ginkgo, feverfew, ginseng, fish oil, or nattokinase, it should be stopped three days before the procedure. Also, if you are on a steroid or another medication that affects the immune system, consult with your physician about the risks and benefits of having the procedure while on the medication to avoid infection. The procedure itself usually involves numbing the toe with the local anesthetic lidocaine, without epinephrine (adrenaline). |
Earl L. Mindell, RPh, PhD with Virginia Hopkins, MA
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| Nearly 2,000 years ago, the Roman doctor Dioscorides, one of the first to write a medical textbook, recommended the herb feverfew {Chrysanthemum parthenium) for headaches. feverfew is still the most effective treatment known for migraines. It is the only medicine that will help migraine headaches without side effects. This member of the daisy family is also called bachelor's buttons. feverfew has undergone much testing and research as a migraine remedy as pharmaceutical companies try to find the active ingredient so they can isolate it and synthesize it. |
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